Scientists Unveil First-Ever Treatment That Halts Devastating Brain-Killing Disease—Could This Be a Miracle Cure?
Imagine hearing that a disease which slowly steals your ability to move, think, and feel—a disease that has haunted families for generations—might finally be slowed down by 75 percent. Sounds like science fiction, right? Well, buckle up, because doctors have just pulled off a groundbreaking feat, treating Huntington’s disease for the very first time with a revolutionary new approach. This rare, inherited neurodegenerative disorder affects about 5 in 100,000 people—and traditionally, it’s been relentless. But now, thanks to a blend of gene therapy and gene silencing, the typical one-year decline in patients is stretched out over four years, offering the tantalizing promise of decades with better quality of life. And honestly, who wouldn’t want to rewrite their genetic destiny? It’s a tale of hope wrapped in cutting-edge science, with real people like 30-year-old Jack May-Davis stepping into a future that suddenly feels a whole lot brighter. Curious to know how this miracle unfolds? LEARN MORE.
Doctors have successfully treated the inherited neurodegenerative disease Huntington’s for the first time with a groundbreaking new treatment.
Huntington’s is a rare health condition affecting around 5 in 100,000 people, which causes the progressive breakdown of nerve cells in the brain. It affects a person’s movement, cognitive abilities, and emotions, which worsen over time.
A mutation of the HTT gene causes Huntington’s disease, and when one parent has the gene mutation but the other doesn’t, each child they have has a 50 per cent chance of inheriting the disease.
While there is no known cure for Huntington’s, a research team that has been working on the treatment made an emotional announcement as they revealed data that showed the disease had slowed by 75 per cent.
The groundbreaking treatment would significantly improve the outlook for many Huntington’s patients, meaning the deterioration you’d expect to see in one year would take four years, allowing patients decades of ‘good quality life’, according to Professor Sarah Tabrizi.
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The research is absolutely groundbreaking (Getty Stock Images)
Symptoms for Huntington’s disease usually emerge when patients are in their thirties or fifties, according to the NHS. However, this new treatment has now provided fresh hope that early treatment could prevent symptoms from developing altogether.
Professor Tabrizi, director of the University College London Huntington’s Disease Centre, described the results as ‘spectacular’, as per BBC News.
“We never in our wildest dreams would have expected a 75 percent slowing of clinical progression,” she said.
The incredible treatment involves a gene therapy given during 12 to 18 hours of extensive brain surgery. In Huntington’s, the gene mutation affects a normal protein, called the huntingtin protein, which is essential in the brain and, when mutated, attacks and kills neurons.
This treatment works by permanently reducing the levels of this toxic protein using genetic medicine, which combines gene therapy and gene silencing technologies.
One person to receive the treatment is 30-year-old Jack May-Davis, a barrister’s clerk who recently got engaged to his partner, Chloe.
Jack carries the Huntington’s gene, which was passed on by his father, Fred and grandmother, Joyce, who both passed away from the illness.
Fred first started exhibiting symptoms in his late 30s, initially changing his movement and behaviour. Eventually, he needed 24-hour care before he died at the age of 54.
Jack said it was ‘really awful and horrible’ to witness his dad go through it all, and he always believed he was heading for the same fate until this ‘absolutely incredible’ breakthrough.
He now feels ‘overwhelmed’ to be able to look into a future that ‘seems a little bit brighter, it does allow me to think my life could be that much longer.’
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